Finnish international Mika Vayrynen will miss Saturday's trip to Burnley after undergoing groin surgery.
Vayrynen sat out the clash at Leicester two weeks ago and was also withdrawn from the Finland squad for the friendly against Denmark earlier this week.United boss Simon Grayson confirmed: "Mika had an op after the Leicester game so he won't be back for Saturday. We wouldn't rush someone back from surgery too quickly."
The boss also confirmed he has a number of other injuries ahead of Saturday's trip to Turf Moor.
"We've got a few lads who only trained for the first time on Thursday after coming daback from various knocks and injuries picked up so we'll have to see how everyone is come the weekend."
Two players who have returned fit and well after international duty are Darren O'Dea and Andy Keogh, who were part of the Irish squad, who qualified for next summer's European Championships.
"They were back with us for the first time on Thursday and are both okay," said the boss. "It's good recognition for everyone and it'll be great if they are involved."